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The Blood-Brain Barrier in Health and Disease
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Authors: William G. Mayhan, Denise M. Arrick
ISBN: 9781615047390
Copyright: 2017
Pages: 78

The blood-brain barrier (BBB) is a complex and dynamic structure that protects the brain from cells within the vasculature, from the immune system and from pathogens. This barrier is present in arterioles, capillaries and venules and is formed at the level of adjacent endothelial cells, which are coupled to astrocytes, microglia, neurons and pericytes. This book focuses on various aspects that account for the formation and maintenance of the BBB, and on disease states that compromise this barrier.

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